SCILOG® NFF+ PS

Semi – Automated NFF with PUPSIT capabilities.

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SCILOG® NFF+ PS

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Categories: automated single-use systems, Equipment, Systems Tags: Parker, Scilog, Single-Use

Description
Additional information

Description

SciLog® NFF+ PS – Semi-Automated Normal Flow Filtration System with PUPSIT

The SciLog® NFF+ PS is a versatile semi-automated Normal Flow Filtration (NFF) system designed to support pre-use and post-use filter integrity testing in GMP-compliant bioprocessing environments. Developed for final fill and bulk fill applications, it helps ensure compliance with EU GMP Annex 1 (2022) requirements by facilitating reliable PUPSIT (Pre-Use Post-Sterilization Integrity Testing).

Additional information

Markets

Biopharmaceutical

Features

Features and Benefits

SIEMENS TIA Portal based control system
Pre-defined options for valve control for final fill process steps, including PUPSIT and post-use integrity
testing
Execute PUPSIT as part of the sequence before continuing to product processing
Visual indicator for valve positioning (open / closed)
Touch-screen HMI with intuitive graphical interface
User configurable alarms and interlocks
Supports the use of an external integrity tester, pressure monitoring and pump
Redundant filtration variant available (SciLog® NFF+ PSR)
Improved efficiency with intuitive manifold installation and programmed process operations.
Error-proofing approach and complete process visibility
Process step selection supporting automated valve control for simplified process operation and minimizing human error
Supports use of an external integrity tester enabling the use of validated equipment.
Sterilizing filter can be integrity tested and validated on the system, before proceeding to filtering; or integrity testing the sterilizing filter post-use directly on the
system / in the assembly – optimizing process steps/resource and minimizing risk of batch losses.
Closed system designed for the cleanroom.

Description

Description

SciLog® NFF+ PS – Semi-Automated Normal Flow Filtration System with PUPSIT

The SciLog® NFF+ PS is a versatile semi-automated Normal Flow Filtration (NFF) system designed to support pre-use and post-use filter integrity testing in GMP-compliant bioprocessing environments. Developed for final fill and bulk fill applications, it helps ensure compliance with EU GMP Annex 1 (2022) requirements by facilitating reliable PUPSIT (Pre-Use Post-Sterilization Integrity Testing).

Additional information

Markets

Biopharmaceutical

Features

Features and Benefits

SIEMENS TIA Portal based control system
Pre-defined options for valve control for final fill process steps, including PUPSIT and post-use integrity
testing
Execute PUPSIT as part of the sequence before continuing to product processing
Visual indicator for valve positioning (open / closed)
Touch-screen HMI with intuitive graphical interface
User configurable alarms and interlocks
Supports the use of an external integrity tester, pressure monitoring and pump
Redundant filtration variant available (SciLog® NFF+ PSR)
Improved efficiency with intuitive manifold installation and programmed process operations.
Error-proofing approach and complete process visibility
Process step selection supporting automated valve control for simplified process operation and minimizing human error
Supports use of an external integrity tester enabling the use of validated equipment.
Sterilizing filter can be integrity tested and validated on the system, before proceeding to filtering; or integrity testing the sterilizing filter post-use directly on the
system / in the assembly – optimizing process steps/resource and minimizing risk of batch losses.
Closed system designed for the cleanroom.