Clariflow-B Mini-Capsule

Encapsulated PES Membrane for Small-Volume Applications

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Description

The Clariflow® B Mini-Capsule is a compact PES capsule designed for pharmaceutical, biopharmaceutical, and biomedical filtration applications requiring high purity and reliable sterile processing performance.

Built with a high-performance PES membrane filter, the capsule delivers excellent flow rates, low protein binding characteristics, and broad chemical compatibility for critical liquid filtration processes. Its disposable design helps reduce contamination risk while simplifying validation and changeover procedures in GMP manufacturing environments.

Clariflow® B Mini-Capsules PES capsule filters are commonly used for sterile filtration, buffer preparation, biological solutions, cell culture media, and laboratory-scale bioprocessing applications.

What is a PES membrane filter?

A PES capsule is a disposable filtration device that uses a polyethersulfone (PES) membrane to remove particles and microorganisms from liquids used in pharmaceutical and biopharmaceutical manufacturing.

PES membrane filters are widely used in sterile processing because they combine high flow rates, low extractables, and low protein binding properties, making them ideal for sensitive biological fluids and critical filtration applications.

Applications of Clariflow® B Mini PES Capsules

Clariflow® B Mini PES membrane filters are used in a wide range of pharmaceutical and biomedical applications, including:

  • Sterile filtration of biological solutions
  • Buffer and media filtration
  • Cell culture preparation
  • Small-volume pharmaceutical processing
  • Laboratory and pilot-scale bioprocessing
  • Filtration of protein-containing solutions
  • Pre-filtration and final filtration workflows

Key Features of the Clariflow® B Mini PES Capsule

  • High-performance polyethersulfone membrane
  • Disposable single-use capsule design
  • Low protein binding characteristics
  • High flow efficiency for reduced processing time
  • Broad chemical compatibility
  • Low extractables and particle shedding
  • GMP and pharmaceutical manufacturing compatibility
  • Compact design for laboratory and small-batch processing

 

Additional information

Markets

Biopharmaceutical

Materials

Polyethersulfone

Retention Ratings

Absolute

Features

Benefits
• High flow rate reduces processing time
• Biologically inert, low protein binding membrane maximizes product yields
• Inherently hydrophilic for cleaner filtrates

Applications
• Sera & Vaccines
• Bacterial Growth Media
• Protein-Containing Preparations
• Parenteral Solutions
• Buffers & Reagents