SciLog® TFF Configurable Systems

Fully Automated GMP Bioprocessing System

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SciLog® TFF Configurable Systems

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Description

SciLog® TFF Configurable System – Modular Tangential Flow Filtration Solution

The SciLog® TFF Configurable System from Parker is a fully automated tangential flow filtration (TFF) system designed to deliver flexibility and performance in bioprocessing applications. Compatible with any brand of hollow fiber or cassette, the system supports both single-use and reusable formats, making it ideal for a wide range of process needs.

Built on a modular system design, this TFF solution can be easily tailored to meet your specific process requirements. Each component is independently validated and integrated using S88-compliant automation practices, ensuring consistency, scalability, and regulatory compliance.

With decades of experience in designing and engineering tangential flow filtration systems, Parker has optimized the configuration process to match the lead times of standard competitor offerings—without compromising customization. The modular design also allows for quick replacement or reconfiguration of components to support evolving process demands.

In addition to configurable systems, SciLog TFF systems are available as commercial off-the-shelf (COTS) solutions for rapid deployment in production environments.

Additional information

Markets

Biopharmaceutical

Features

Features and Benefits

  • Capable of processing at flow rates of 0.2-83 L/min depending on format
  • Operating pressure up to 60 PSI
  • Suitable for ultrafiltration (3kD-750kD) and microfiltration (750 kD- 0.65μm) applications and comes standard with diafiltration capabilities
  • Recipe based control of process in either discrete steps or batch mode
  • Touch-screen HMI with intuitive graphical interface
  • Fully programmable alarms and interlocks
  • 21CFR Part 11 Ready
  • Easy integration into DCS/SCADA systems
  • Direct connection to scales and mixers or integration via DCS
  • User access level control via local or active directory
  • Minimizes retentate vessel size using batch fed concentration mode
  • Systems and manifolds designed in tandem to minimize hold up
  • Smallest footprint on the market